作者
Suzanne L. Topalian,F. Stephen Hodi,Julie R. Brahmer,Scott Gettinger,David C. Smith,David F. McDermott,John D. Powderly,Richard D. Carvajal,Jeffrey A. Sosman,Michael B. Atkins,Philip D. Leming,David R. Spigel,Scott Antonia,Leora Horn,Charles G. Drake,Drew M. Pardoll,Lieping Chen,William H. Sharfman,Robert A. Anders,Janis M. Taube,Tracee L. McMiller,Haiying Xu,Alan J. Korman,Maria Jure–Kunkel,Shruti Agrawal,D. G. McDonald,Georgia Kollia,Ashok Gupta,Jon M. Wigginton,Mario Sznol
摘要
Blockade of programmed death 1 (PD-1), an inhibitory receptor expressed by T cells, can overcome immune resistance. We assessed the antitumor activity and safety of BMS-936558, an antibody that specifically blocks PD-1.