芳香烃受体
结肠炎
平衡(能力)
免疫学
受体
化学
医学
内科学
物理疗法
生物化学
转录因子
基因
作者
Shu Wang,Ying Xu,Lu Wang,Junjie Lin,Chenjing Xu,Xiaojing Zhao,Hongjie Zhang
出处
期刊:Inflammatory Bowel Diseases
[Oxford University Press]
日期:2024-03-02
卷期号:30 (9): 1546-1555
被引量:1
摘要
Tolerogenic dendritic cells (TolDCs) have been evidenced to trigger regulatory T cell's (Treg's) differentiation and be involved in the pathogenesis of Crohn's disease (CD). Aryl hydrocarbon receptor (AhR) plays a crucial role in the differentiation of TolDCs, although the mechanism remains vague. This study aimed to evaluate the role of AhR in TolDCs formation, which may affect Th17/Treg balance in CD.
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