Probable Acquired QTc Prolongation and Subsequent Torsades de Pointes Attributable to Quetiapine

Article AbstractBecause this piece does not have an abstract, we have provided for your benefit the first 3 sentences of the full text.Quetiapine is a commonly prescribed second-generation antipsychotic with a wide range of uses in psychiatry. Compared to first-generation high-potency antipsychotics such as thioridazine and high-dose intravenous haloperidol, medications in the newer second-generation antipsychotic class (of which quetiapine belongs) are thought to have a lower risk of prolonging the corrected QT (QTc) interval, torsades de pointes, and sudden death. Among the second-generation antipsychotics of its class, quetiapine is known to prolong the QTc interval in modest levels and less so than ziprasidone and sertindole.