量子点
石墨烯
多路复用
光电子学
材料科学
红外线的
纳米技术
光学
物理
生物
生物信息学
作者
Alina Valimukhametova,Olivia Fannon,Ugur C. Topkiran,Abby Dorsky,Olivia Sottile,Roberto González-Rodríguez,Jeffery L. Coffer,Anton V. Naumov
出处
期刊:2D materials
[IOP Publishing]
日期:2024-01-19
卷期号:11 (2): 025009-025009
被引量:1
标识
DOI:10.1088/2053-1583/ad1c6e
摘要
Due to high tissue penetration depth and low autofluorescence backgrounds, near-infrared (NIR) fluorescence imaging has recently become an advantageous diagnostic technique used in a variety of fields. However, most of the NIR fluorophores do not have therapeutic delivery capabilities, exhibit low photostabilities, and raise toxicity concerns. To address these issues, we developed and tested five types of biocompatible graphene quantum dots (GQDs) exhibiting spectrally-separated fluorescence in the NIR range of 928-1053 nm with NIR excitation. Their optical properties in the NIR are attributed to either rare-earth metal dopants (Ho-NGQDs, Yb-NGQDs, Nd-NGQDs) or defect-states (nitrogen doped GQDS (NGQDs), reduced graphene oxides) as verified by Hartree-Fock calculations. Moderate up to 1.34% quantum yields of these GQDs are well-compensated by their remarkable >4 h photostability. At the biocompatible concentrations of up to 0.5-2 mg ml
科研通智能强力驱动
Strongly Powered by AbleSci AI