青枯菌
生物
系统发育树
青枯病
遗传学
致病性
基因组
鉴定(生物学)
系统发育学
进化生物学
病菌
计算生物学
毒力
基因
微生物学
生态学
作者
Stéphane Genin,Timothy P. Denny
出处
期刊:Annual Review of Phytopathology
[Annual Reviews]
日期:2012-09-08
卷期号:50 (1): 67-89
被引量:509
标识
DOI:10.1146/annurev-phyto-081211-173000
摘要
Ralstonia solanacearum is a major phytopathogen that attacks many crops and other plants over a broad geographical range. The extensive genetic diversity of strains responsible for the various bacterial wilt diseases has in recent years led to the concept of an R. solanacearum species complex. Genome sequencing of more than 10 strains representative of the main phylogenetic groups has broadened our knowledge of the evolution and speciation of this pathogen and led to the identification of novel virulence-associated functions. Comparative genomic analyses are now opening the way for refined functional studies. The many molecular determinants involved in pathogenicity and host-range specificity are described, and we also summarize current understanding of their roles in pathogenesis and how their expression is tightly controlled by an intricate virulence regulatory network.
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