The Alcohol Harm Paradox in Periodontitis

全国健康与营养检查调查 狂饮 优势比 人口学 医学 置信区间 逻辑回归 牙周炎 调解 环境卫生 毒物控制 伤害预防 牙科 内科学 人口 法学 社会学 政治学
作者
Leandro Machado Oliveira,Fabrício Batistin Zanatta,Susilena Arouche Costa,Thayná Regina Pelissari,Sebastian‐Edgar Baumeister,Flávio Fernando Demarco,Gustavo G. Nascimento
出处
期刊:Journal of Dental Research [SAGE]
卷期号:103 (6): 605-611 被引量:2
标识
DOI:10.1177/00220345241235614
摘要

Individuals of lower socioeconomic position (SEP) experience a greater rate of alcohol-related harms, yet they consume equal or lower amounts of alcohol than higher-SEP individuals. This phenomenon, called the “alcohol harm paradox” (AHP), gained attention recently, and different mechanisms have been proposed to explain it. Since both SEP and alcohol have been suggested to be associated with periodontitis risk, we conducted a secondary analysis using data from the National Health and Nutrition Examination Survey 2011 to 2012 and 2013 to 2014 cycles, aiming to examine 1) whether the association between alcohol consumption and periodontitis is modified by SEP and 2) the extent to which the effect of SEP inequalities on periodontitis is mediated by and/or interacts with alcohol consumption. We set educational attainment as the main SEP proxy and tested the poverty income ratio in subsequent sensitivity analyses. Effect measure modification analysis was employed, considering heavy drinking as exposure, and causal mediation analysis based on the potential outcome’s framework decomposed the effect of SEP on periodontitis in proportions attributable to mediation and interaction. Models were fitted using binary logistic regression and adjusted for sex, ethnicity, age, body mass index, smoking status, diabetes, binge drinking, and regular preventive dental visits. The analytical sample comprised 4,057 participants. After adjusting for covariates, less educated heavy drinkers presented 175% (odds ratio, 2.75; 95% confidence interval [CI], 2.04–3.72) higher odds of periodontitis than their counterparts, and super-additive associations were found (relative excess risk due to interaction: 1.35; 95% CI, 0.49–2.20). Additionally, −69.5% (95% CI, −122.1% to −16.8%) of the effects of education on periodontitis were attributable to interaction with heavy drinking, consistent with the AHP. No contribution was found for the mechanism of mediation. Heavy drinking disproportionately impacts the occurrence of periodontitis in lower-SEP individuals. Lower-SEP individuals seem to experience differential effects of heavy drinking on periodontitis.
最长约 10秒,即可获得该文献文件

科研通智能强力驱动
Strongly Powered by AbleSci AI
科研通是完全免费的文献互助平台,具备全网最快的应助速度,最高的求助完成率。 对每一个文献求助,科研通都将尽心尽力,给求助人一个满意的交代。
实时播报
刚刚
1秒前
Jirobai发布了新的文献求助10
1秒前
FashionBoy应助淅沥采纳,获得10
1秒前
万能图书馆应助冰红茶采纳,获得10
1秒前
1秒前
2秒前
BILNQPL完成签到,获得积分10
2秒前
similar完成签到 ,获得积分10
2秒前
科研通AI5应助干净傲儿采纳,获得10
2秒前
烨然完成签到,获得积分10
2秒前
3秒前
3秒前
顺利的愫发布了新的文献求助10
3秒前
3秒前
3秒前
勤恳纸鹤发布了新的文献求助10
3秒前
苏卿应助123HJJJKJJKJK采纳,获得10
4秒前
4秒前
赘婿应助demo1采纳,获得10
4秒前
5秒前
afv发布了新的文献求助10
5秒前
咕咕完成签到,获得积分20
5秒前
BILNQPL发布了新的文献求助10
5秒前
殴打阿达完成签到,获得积分10
6秒前
6秒前
6秒前
跳跳狗发布了新的文献求助10
7秒前
Jirobai完成签到,获得积分10
7秒前
思源应助玻尿酸采纳,获得10
7秒前
聆风发布了新的文献求助10
7秒前
聪明虎完成签到,获得积分10
7秒前
ciooli发布了新的文献求助10
8秒前
chen完成签到,获得积分10
8秒前
卓惜筠发布了新的文献求助10
8秒前
8秒前
8秒前
乐乐应助成就的念双采纳,获得10
9秒前
gb完成签到 ,获得积分10
9秒前
dw发布了新的文献求助30
9秒前
高分求助中
Continuum Thermodynamics and Material Modelling 3000
Production Logging: Theoretical and Interpretive Elements 2700
Mechanistic Modeling of Gas-Liquid Two-Phase Flow in Pipes 2500
Kelsen’s Legacy: Legal Normativity, International Law and Democracy 1000
Handbook on Inequality and Social Capital 800
Conference Record, IAS Annual Meeting 1977 610
Interest Rate Modeling. Volume 3: Products and Risk Management 600
热门求助领域 (近24小时)
化学 材料科学 生物 医学 工程类 有机化学 生物化学 物理 纳米技术 计算机科学 内科学 化学工程 复合材料 基因 遗传学 物理化学 催化作用 量子力学 光电子学 冶金
热门帖子
关注 科研通微信公众号,转发送积分 3546979
求助须知:如何正确求助?哪些是违规求助? 3123961
关于积分的说明 9357531
捐赠科研通 2822555
什么是DOI,文献DOI怎么找? 1551574
邀请新用户注册赠送积分活动 723561
科研通“疑难数据库(出版商)”最低求助积分说明 713801