In Vivo Mapping of Deep Tissue pO ₂ in a Murine Model of Peripheral Artery Disease by Noninvasive ¹⁹ F MR Relaxometry

HomeArteriosclerosis, Thrombosis, and Vascular BiologyVol. 43, No. 4In Vivo Mapping of Deep Tissue pO2 in a Murine Model of Peripheral Artery Disease by Noninvasive 19F MR Relaxometry No AccessLetterRequest AccessFull TextAboutView Full TextView PDFView EPUBSections ToolsAdd to favoritesDownload citationsTrack citationsPermissions ShareShare onFacebookTwitterLinked InMendeleyReddit Jump toNo AccessLetterRequest AccessFull TextIn Vivo Mapping of Deep Tissue pO2 in a Murine Model of Peripheral Artery Disease by Noninvasive 19F MR Relaxometry Nicolas Stumpe, Tuba Güden-Silber, Rebekka Schneckmann, Katharina Wolters, Hildo Lamb, Maria Grandoch and Ulrich Flögel Nicolas StumpeNicolas Stumpe https://orcid.org/0000-0002-8708-7844 Institute for Molecular Cardiology, Heinrich Heine University, Düsseldorf, Germany (N.S., T.G.-S., U.F.). Cardiovascular Imaging, University Medical Center, Leiden, the Netherlands (N.S., H.L.). *N. Stumpe and T. Güden-Silber contributed equally. Search for more papers by this author , Tuba Güden-SilberTuba Güden-Silber https://orcid.org/0000-0002-2668-9542 Institute for Molecular Cardiology, Heinrich Heine University, Düsseldorf, Germany (N.S., T.G.-S., U.F.). *N. Stumpe and T. Güden-Silber contributed equally. Search for more papers by this author , Rebekka SchneckmannRebekka Schneckmann https://orcid.org/0000-0001-8692-309X Institute for Translational Pharmacology, Heinrich Heine University, Düsseldorf, Germany (R.S., K.W., M.G.). Search for more papers by this author , Katharina WoltersKatharina Wolters Institute for Translational Pharmacology, Heinrich Heine University, Düsseldorf, Germany (R.S., K.W., M.G.). Search for more papers by this author , Hildo LambHildo Lamb https://orcid.org/0000-0002-6969-2418 Cardiovascular Imaging, University Medical Center, Leiden, the Netherlands (N.S., H.L.). Search for more papers by this author , Maria GrandochMaria Grandoch https://orcid.org/0000-0002-4382-1947 Institute for Translational Pharmacology, Heinrich Heine University, Düsseldorf, Germany (R.S., K.W., M.G.). Search for more papers by this author and Ulrich FlögelUlrich Flögel Correspondence to: Ulrich Flögel, PhD, Institute for Molecular Cardiology, Heinrich Heine University, Universitätsstraße 1, 40225 Düsseldorf, Germany. Email E-mail Address: [email protected] https://orcid.org/0000-0001-7181-4392 Institute for Molecular Cardiology, Heinrich Heine University, Düsseldorf, Germany (N.S., T.G.-S., U.F.). Search for more papers by this author Originally published9 Feb 2023https://doi.org/10.1161/ATVBAHA.122.318548Arteriosclerosis, Thrombosis, and Vascular Biology. 2023;43:597–598"In Vivo Mapping of Deep Tissue pO2 in a Murine Model of Peripheral Artery Disease by Noninvasive 19F MR Relaxometry." Arteriosclerosis, Thrombosis, and Vascular Biology, 43(4), pp. 597–598Footnotes*N. Stumpe and T. Güden-Silber contributed equally.For Sources of Funding and Disclosures, see page 598.Correspondence to: Ulrich Flögel, PhD, Institute for Molecular Cardiology, Heinrich Heine University, Universitätsstraße 1, 40225 Düsseldorf, Germany. Email [email protected]deReferences1. Thomas SR, Pratt RG, Millard RW, Samaratunga RC, Shiferaw Y, Clark LC, Hoffmann RE. Evaluation of the influence of the aqueous phase bioconstituent environment on the F-19 T1 of perfluorocarbon blood substitute emulsions.J Magn Reson Imaging. 1994; 4:631–635. doi: 10.1002/jmri.1880040421CrossrefMedlineGoogle Scholar2. Flögel U, Ding Z, Hardung H, Jander S, Reichmann G, Jacoby C, Schubert R, Schrader J. In vivo monitoring of inflammation after cardiac and cerebral ischemia by fluorine magnetic resonance imaging.Circulation. 2008; 118:140–148. doi: 10.1161/CIRCULATIONAHA.107.737890LinkGoogle Scholar3. Schneckmann R, Suvorava T, Hundhausen C, Schuler D, Lorenz C, Freudenberger T, Kelm M, Fischer JW, Flögel U, Grandoch M. Endothelial hyaluronan synthase 3 augments postischemic arteriogenesis through CD44/eNOS signaling.Arterioscler Thromb Vasc Biol. 2021; 41:2551–2562. doi: 10.1161/ATVBAHA.121.315478LinkGoogle Scholar Previous Back to top Next FiguresReferencesRelatedDetails April 2023Vol 43, Issue 4 Advertisement Article InformationMetrics © 2023 American Heart Association, Inc.https://doi.org/10.1161/ATVBAHA.122.318548PMID: 36756882 Originally publishedFebruary 9, 2023 Keywordsecho-planar imagingperipheral arterial diseasehypoxiafluorinemitral valve insufficiencymagnetic resonance imagingPDF download Advertisement SubjectsMagnetic Resonance Imaging (MRI)Peripheral Vascular DiseaseVascular Biology