Relationship between dopamine and obesity

Environmental, genetic and other factors can lead to obesity, in which the relationship between dopamine and obesity becomes a hot topic. Palatable food can activate the brain reward system and increase dopamine release that makes the body get satisfaction and pleasure, and feeding addiction leads to obesity; thus the deficiency of dopamine D2 receptor causes reward deficiency syndrome. Excessive feeding to compensate for the reduced sense of pleasure and satisfaction, leads to obesity; in addition, dopamine dysfunction can also reduce body activity.Exploring the relationship between dopamine and obesity, is beneficial to further explain the pathogenesis of obesity and to provide new ideas and methods for the treatment of obesity. Key words: Dopamine; Obesity; Brain reward system; Treatment