New guidelines for embryo and stem cell research

This year the International Society for Stem Cell Research (ISSCR) updated its Guidelines for Stem Cell Research and Clinical Translation. Here we discuss some key changes to the 2016 guidelines, and the need for such changes in light of advances in research using models of human development. Christine Mummery and Eric Anthony discuss some key changes to the ISSCR Guidelines for Stem Cell Research and Clinical Translation, which concern, among other experimental procedures, the culturing of human embryos, genome editing and mitochondrial replacement techniques.