生物材料
组织工程
材料科学
生物相容性
生物相容性材料
纳米技术
再生(生物学)
生物医学工程
智能材料
压电
生化工程
工程类
细胞生物学
生物
复合材料
冶金
作者
Amit Nain,Srishti Chakraborty,Snigdha Roy Barman,Pratik Gavit,Sushma Indrakumar,Akhilesh Agarwal,Zong‐Hong Lin,Kaushik Chatterjee
出处
期刊:Biomaterials
[Elsevier]
日期:2024-03-01
卷期号:: 122528-122528
被引量:6
标识
DOI:10.1016/j.biomaterials.2024.122528
摘要
Piezoelectric biomaterials have demonstrated significant potential in the past few decades to heal damaged tissue and restore cellular functionalities. Herein, we discuss the role of bioelectricity in tissue remodeling and explore ways to mimic such tissue-like properties in synthetic biomaterials. In the past decade, biomedical engineers have adopted emerging functional biomaterials-based tissue engineering approaches using innovative bioelectronic stimulation protocols based on dynamic stimuli to direct cellular activation, proliferation, and differentiation on engineered biomaterial constructs. The primary focus of this review is to discuss the concepts of piezoelectric energy harvesting, piezoelectric materials, and their application in soft (skin and neural) and hard (dental and bone) tissue regeneration. While discussing the prospective applications as an engineered tissue, an important distinction has been made between piezoceramics, piezopolymers, and their composites. The superiority of piezopolymers over piezoceramics to circumvent issues such as stiffness mismatch, biocompatibility, and biodegradability are highlighted. We aim to provide a comprehensive review of the field and identify opportunities for the future to develop clinically relevant to state-of-the-art biomaterials for personalized and remote health care.
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