广谱
抗生素
单核细胞
炎症反应
肺
免疫学
医学
微生物学
炎症
生物
化学
内科学
组合化学
作者
Patrick J. Dörner,Ivo Röwekamp,Harithaa Anandakumar,Bastian Opitz
出处
期刊:CERN European Organization for Nuclear Research - Zenodo
日期:2023-04-18
标识
DOI:10.5281/zenodo.7841983
摘要
Code and data for the preprint "Clinically used broad-spectrum antibiotics compromise inflammatory monocyte-dependent antibacterial defense in the lung". Metagenomic analysis - uses `targets` (workflow manager) and `renv` (environment manager) R packages. - calling `targets::tar_make()`, once the environment is configured using renv and a separate project has been created (with the exact file structure including the data), should run the entire pipeline, creating a _targets folder with all the .rds files - independent objects can be explored using `targets::tar_load(obj)` or `targets::tar_read(plot)` Targets user manual for more information. Preprocessing/QC scripts can be provided upon reasonable request.
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