香豆素
药效团
癌症
化学
癌细胞
计算生物学
药理学
组合化学
生物化学
生物
遗传学
有机化学
作者
Xufeng Song,Jing Fan,Lan Liu,Xiaofeng Liu,Feng Gao
标识
DOI:10.1002/ardp.202000025
摘要
Abstract Cancer can invade or spread to almost all parts of the body. The increasing morbidity and high mortality of cancer create a great demand for the development of novel anticancer drugs. Coumarin derivatives are ubiquitous in nature and can readily interact with diverse enzymes and receptors in cancer cells via weak bond interactions; hence, coumarin is a highly privileged pharmacophore for the development of novel anticancer agents. This review will focus on the recent development of coumarin hybrids as potential anticancer agents covering articles published from 2019 to 2020.
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