纳米技术
药物输送
纳米颗粒
生物医学
微乳液
模板
材料科学
纳米医学
药剂学
工程类
生物信息学
化学工程
肺表面活性物质
医学
生物
药理学
作者
Fang Fang,Min Li,Jinfeng Zhang,Chun‐Sing Lee
出处
期刊:ACS materials letters
[American Chemical Society]
日期:2020-04-09
卷期号:2 (5): 531-549
被引量:71
标识
DOI:10.1021/acsmaterialslett.0c00078
摘要
Organic nanoparticles with intriguing features have attracted widespread attention for various biomedical applications, such as disease diagnosis, drug delivery, bioimaging, and cancer therapy. Therefore, considerable efforts have been made to develop different strategies for constructing organic nanoparticles with distinct morphologies and properties. In this Review, we will briefly introduce the building blocks and driving forces employed for organic nanoparticle formation. The primary focus will be placed on summarizing different preparation strategies, including self-assembly, microemulsion, layer-by-layer assembly, particle replication in nonwetting templates, electrospraying, and microfluidics. Moreover, numerous surface modification approaches for organic nanoparticles will also be highlighted, followed by a strategic outlook for next-generation fabrication approaches. We believe that the above topics will appeal to researchers from different fields including chemical, materials, and biological sciences, as well as pharmaceutics.
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