多金属氧酸盐
化学
癌症治疗
纳米复合材料
药物输送
光热治疗
氧化物
癌症
纳米技术
组合化学
有机化学
内科学
催化作用
医学
材料科学
作者
Gabriela Guedes,Shiqi Wang,Hélder A. Santos,Filipa L. Sousa
标识
DOI:10.1002/ejic.202000066
摘要
Polyoxometalates (POMs) are metal‐oxide inorganic clusters, mostly anionic, where the metal is usually a transition metal (such as V, W, or Mo). Owing to their great variety of structures and large range of molecular dimensions, POMs have attracted considerable attention over the years. The high solubility in water together with the extent of their redox chemistry make POMs and their composites very versatile materials that find many applications in the biomedical field such as drug delivery systems or anti‐viral and anti‐tumoural agents. While the antitumoural activity of POMs and their derivatives is well documented, their application in emergent cancer therapies has not been addressed. This review presents the application of POM‐based composites as photothermal agents, radiosensitisers, and biosensors. The latest advances in the design of novel POM nanocomposites for cancer theranostics are also highlighted.
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