Mini review: The FDA‐approved prescription drugs that induce ovulation in women with ovulatory problems

排卵 多囊卵巢 不育 促黄体激素 医学 卵泡期 无排卵 促卵泡激素 促排卵 月经周期 促性腺激素 激素 妇科 内分泌学 内科学 生物 怀孕 胰岛素 胰岛素抵抗 遗传学
作者
Chunlei Sun,Xi Rong,Yongqin Cai,Song Qiu,Maryam Farzaneh
出处
期刊:Drug Development Research [Wiley]
卷期号:81 (7): 815-822 被引量:3
标识
DOI:10.1002/ddr.21687
摘要

Abstract Infertility is defined as not being able to become pregnant after 12 months or more of unprotected sexual intercourse. Female infertility as a serious health issue can result from ovulation disorders, menstrual cycle problems, structural problems, and environmental factors. Ovulation occurs once a month between the time of menarche and menopause. The release of a mature egg from the ovary is controlled with the hypothalamic‐pituitary‐ovarian axis. Several hormones such as gonadotropin‐releasing hormone (GnRH), FSH (follicle‐stimulating hormone), LH (luteinizing hormone), estrogen, and progesterone play fundamental roles in the ovulation process. Both FSH and LH are the main treatment for women with ovulation disorders. Depending on the reasons for infertility, several different types of treatment are available for infertile women. Fertility drugs as an important part of treatment work like the natural hormones to treat infertility. Several fertility drugs can regulate ovulation and the release of an egg from the ovary in women with polycystic ovary syndrome (PCOS) or undergoing in vitro fertilization (IVF) treatment. This mini‐review is about the FDA‐approved prescription drugs that induce ovulation in women with ovulatory problems.

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