标准化
仪表(计算机编程)
成像体模
医学物理学
可靠性(半导体)
生物医学工程
再现性
材料科学
计算机科学
医学
核医学
物理
化学
功率(物理)
量子力学
操作系统
色谱法
作者
Lina Hacker,Heidrun Wabnitz,Antonio Pifferi,T. Joshua Pfefer,Brian W. Pogue,Sarah E. Bohndiek
标识
DOI:10.1038/s41551-022-00890-6
摘要
A lack of accepted standards and standardized phantoms suitable for the technical validation of biophotonic instrumentation hinders the reliability and reproducibility of its experimental outputs. In this Perspective, we discuss general criteria for the design of tissue-mimicking biophotonic phantoms, and use these criteria and state-of-the-art developments to critically review the literature on phantom materials and on the fabrication of phantoms. By focusing on representative examples of standardization in diffuse optical imaging and spectroscopy, fluorescence-guided surgery and photoacoustic imaging, we identify unmet needs in the development of phantoms and a set of criteria (leveraging characterization, collaboration, communication and commitment) for the standardization of biophotonic instrumentation.
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