Thermally induced silane dehydrocoupling on porous silicon nanoparticles for ultra-long-acting drug release

An ultra-long-acting drug-releasable (>2 weeks) nano-formulation based on porous silicon nanoparticles (pSiNPs) that are prepared using the thermally induced silane dehydrocoupling, an amphiphilic lipid-coating, and is disclosed for the first time.