输送带
纳米颗粒
材料科学
纳米技术
激光器
带式输送机
生物相容性材料
光电子学
光学
生物医学工程
机械工程
物理
工程类
作者
Xiaoshuai Liu,You Wu,Xiaohao Xu,Yuchao Li,Yao Zhang,Baojun Li
出处
期刊:Small
[Wiley]
日期:2019-10-21
卷期号:15 (50)
被引量:23
标识
DOI:10.1002/smll.201905209
摘要
Abstract The bidirectional transport of nanoparticles and biological cells is of great significance in efficient biological assays and precision cell screening, and can be achieved with optical conveyor belts in a noncontact and noninvasive manner. However, implantation of these belts into biological systems can present significant challenges owing to the incompatibility of the artificial materials. In this work, an optical conveyor belt assembled from natural biological cells is proposed. The diameter of the belt (500 nm) is smaller than the laser wavelength (980 nm) and, therefore, the evanescent wave stably traps the nanoparticles and cells on the belt surface. By adjusting the relative power of the lasers injected into the belt, the particles or cells can be bidirectionally transported along the bio‐conveyor belt. The experimental results are numerically interpreted and the transport velocities are investigated based on simulations. Further experiments show that the bio‐conveyor belt can also be assembled with mammalian cells and then applied to dynamic cell transport in vivo. The bio‐conveyor belt might provide a noninvasive and biocompatible tool for biomedical assays, drug delivery, and biological nanoarchitectonics.
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