The structural feature and biological function of nuclear transcription factor C/EBPβ

The transcription factor C/EBPβ belongs to the gene regulator family of the CCAAT/ enhancer binding proteins,which are encoded by an intronless gene as a bZIP transcription factor. C/ EBPβ plays important roles in numerous biological function by regulating the transcripition of genes, including the cell differentiation, tumorigenesis, inflammation, energy metabolism and other important life activities.At the same time, the function of C/EBPβ is regulated by proteolysis, phosphorylation , interaction between proteins, etc. In this paper, the structural feature and biological function of C/EBPβ and their research progresses were reviewed. Key words: C/EBPβ;  Transcription factor