分子印迹聚合物
电化学
聚合物
分子印迹
化学
纳米技术
生物传感器
组合化学
色谱法
材料科学
有机化学
催化作用
电极
选择性
物理化学
作者
D. Hernández-Ramírez,Miriam Franco Guzmán,Israel S. Ibarra,Giaan Arturo Álvarez‐Romero,L. E. Rebolledo-Perales
出处
期刊:Journal of The Electrochemical Society
[The Electrochemical Society]
日期:2024-06-28
卷期号:171 (7): 077506-077506
标识
DOI:10.1149/1945-7111/ad5d1f
摘要
Glucose is the principal source of energy for humans and its quantification in physiological samples can diagnose or prevent diseases. Commonly, glucose determination is based on spectrophotometric-enzymatic techniques, but since at least a decade ago, electroanalytical strategies have emerged as promising alternatives providing accuracy and precision in the determination of biomolecules. This review focuses on the development of non-enzymatic methodologies based on modified electrochemical sensors with molecularly imprinted polymers (MIPs) for glucose detection sensors in physiological samples (blood, saliva, and urine). The trends in the construction of non-enzymatic sensors base on MIP combine with materials such as carbonaceous materials, metal nanoparticles, and polymers improving their electrocatalytic properties and analytical parameters of the electro-analytical methodologies developed. Glassy carbon electrodes, carbon paste electrodes, and screen-printed electrodes are the main transductors modified with MIP for the electrochemical oxidation of glucose, and the maximum anodic peak current is taken to the analytical signal. In all reported non-enzymatic sensors, the presence of the MIP improved glucose determination compared to the bare working electrode. The reported results demonstrated that this electroanalytical approach represents a viable alternative for fast and confident analysis of the glucose molecule overcoming the drawbacks presented by enzymatic sensors.
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