底漆(化妆品)
计算生物学
生物
遗传学
化学
有机化学
作者
Elijah C. Mehlferber,Gontran Arnault,Bishnu P. Joshi,Laila P. Partida‐Martínez,Kathryn A. Patras,Marie Simonin,Britt Koskella
出处
期刊:Nature microbiology
日期:2024-10-30
卷期号:9 (11): 2765-2773
标识
DOI:10.1038/s41564-024-01827-2
摘要
The design and use of synthetic communities, or SynComs, is one of the most promising strategies for disentangling the complex interactions within microbial communities, and between these communities and their hosts. Compared to natural communities, these simplified consortia provide the opportunity to study ecological interactions at tractable scales, as well as facilitating reproducibility and fostering interdisciplinary science. However, the effective implementation of the SynCom approach requires several important considerations regarding the development and application of these model systems. There are also emerging ethical considerations when both designing and deploying SynComs in clinical, agricultural or environmental settings. Here we outline current best practices in developing, implementing and evaluating SynComs across different systems, including a focus on important ethical considerations for SynCom research. Here the authors outline best practices for the development, implementation and evaluation of synthetic microbial communities (or SynComs) across different systems.
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