生物
清脆的
DNA
劈理（地质）
遗传学
计算生物学
基因
古生物学
断裂（地质）
作者
Chendi Zhang,F. Chen,Feng Wang,Haijiang Xu,Jialin Xue,Zhuang Li
标识
DOI：10.1016/j.molcel.2024.06.033
摘要
The metagenome-derived type I-E and type I-F variant CRISPR-associated complex for antiviral defense (Cascade) complexes, fused with HNH domains, precisely cleave target DNA, representing recently identified genome editing tools. However, the underlying working mechanisms remain unknown. Here, structures of type I-F
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