Efficacy of remote ischemic conditioning does not differ between men and women: A secondary analysis of the RICAMIS study

医学 置信区间 优势比 改良兰金量表 临床终点 逻辑回归 内科学 冲程(发动机) 血压 糖尿病 随机化 随机对照试验 物理疗法 缺血性中风 缺血 内分泌学 机械工程 工程类
作者
Huiling Qu,Xiao‐Yu Sun,Yu Cui,Yina Zhang,Dawei Chen
出处
期刊:European Journal of Neurology [Wiley]
卷期号:30 (7): 2022-2030 被引量:4
标识
DOI:10.1111/ene.15805
摘要

Abstract Background and Purpose The present study aimed to determine sex difference in clinical outcomes after Remote Ischemic Conditioning for Acute Moderate Ischemic Stroke (RICAMIS). Methods In this secondary analysis of the RICAMIS study, eligible patients aged 18 years or older with acute moderate ischemic stroke who received remote ischemic conditioning (RIC) within 48 h of stroke onset were divided into two groups: men and women. The primary endpoint was an excellent functional outcome, defined as a modified Rankin Scale score of 0–1 at 90 days. Binary logistic regression analyses and generalized linear models were used. Results Of 1707 eligible patients, 34% (579) were women. Women had a higher burden of hypertension and diabetes, and less alcohol and smoking consumption than men. The mean systolic blood pressure and blood glucose level at randomization were higher in women than in men. Compared with the control group, RIC was associated with an increased rate of primary endpoint in men (unadjusted odds ratio [OR] = 1.277; 95% confidence interval [CI] 0.933–1.644; p = 0.057) and women (unadjusted OR = 1.454; 95% CI 1.040–2.032; p = 0.028). Furthermore, a higher absolute risk difference in primary endpoint between control and RIC groups was found in women (9.2%) than in men (5.7%), but there was no significant interaction effect between sex and intervention on primary outcome ( p interaction = 0.545). Conclusion Compared with men, women may have a higher probability of excellent functional outcomes at 90 days in the RIC group than in the control group; however, no interaction effect between sex and intervention was found.
最长约 10秒,即可获得该文献文件

科研通智能强力驱动
Strongly Powered by AbleSci AI
更新
PDF的下载单位、IP信息已删除 (2025-6-4)

科研通是完全免费的文献互助平台,具备全网最快的应助速度,最高的求助完成率。 对每一个文献求助,科研通都将尽心尽力,给求助人一个满意的交代。
实时播报
苗条梦玉发布了新的文献求助10
1秒前
1秒前
2秒前
椰汁味完成签到,获得积分10
3秒前
CC悟了发布了新的文献求助10
5秒前
木子发布了新的文献求助10
5秒前
7秒前
上官若男应助南音采纳,获得10
7秒前
大爷完成签到 ,获得积分10
8秒前
牢大完成签到 ,获得积分10
9秒前
9秒前
领导范儿应助wangxiaobin采纳,获得10
9秒前
852应助翁雁丝采纳,获得10
9秒前
11秒前
徐振阳发布了新的文献求助10
11秒前
Dilmma发布了新的文献求助20
11秒前
May发布了新的文献求助10
14秒前
15秒前
16秒前
BatFaith发布了新的文献求助10
16秒前
18秒前
奋斗的萝发布了新的文献求助10
18秒前
18秒前
19秒前
nkpdsy发布了新的文献求助10
21秒前
21秒前
notsoeasy发布了新的文献求助10
21秒前
化学小学生完成签到,获得积分10
22秒前
玉儿发布了新的文献求助10
22秒前
田様应助忱麓裔采纳,获得10
23秒前
Lucas应助May采纳,获得10
23秒前
量子星尘发布了新的文献求助10
24秒前
善学以致用应助景清采纳,获得10
24秒前
漂亮的秋天完成签到,获得积分10
25秒前
hjy发布了新的文献求助10
26秒前
默默完成签到 ,获得积分10
26秒前
南音发布了新的文献求助10
28秒前
29秒前
英姑应助奋斗的萝采纳,获得10
29秒前
orixero应助该换手机采纳,获得10
29秒前
高分求助中
A new approach to the extrapolation of accelerated life test data 1000
Picture Books with Same-sex Parented Families: Unintentional Censorship 700
ACSM’s Guidelines for Exercise Testing and Prescription, 12th edition 500
Nucleophilic substitution in azasydnone-modified dinitroanisoles 500
不知道标题是什么 500
Indomethacinのヒトにおける経皮吸収 400
Phylogenetic study of the order Polydesmida (Myriapoda: Diplopoda) 370
热门求助领域 (近24小时)
化学 材料科学 医学 生物 工程类 有机化学 生物化学 物理 内科学 纳米技术 计算机科学 化学工程 复合材料 遗传学 基因 物理化学 催化作用 冶金 细胞生物学 免疫学
热门帖子
关注 科研通微信公众号,转发送积分 3975693
求助须知:如何正确求助?哪些是违规求助? 3520019
关于积分的说明 11200635
捐赠科研通 3256410
什么是DOI,文献DOI怎么找? 1798255
邀请新用户注册赠送积分活动 877490
科研通“疑难数据库(出版商)”最低求助积分说明 806390