Biocatalytic Synthesis of Quercetin 3‐O‐Glucoside‐7‐O‐Rhamnoside by Metabolic Engineering of Escherichia coli

ChemBioChemVolume 14, Issue 18 p. 2418-2422 Communication Biocatalytic Synthesis of Quercetin 3-O-Glucoside-7-O-Rhamnoside by Metabolic Engineering of Escherichia coli Jonathon Roepke, Jonathon Roepke Department of Plant Agriculture, University of Guelph, 50 Stone Road E., Guelph, ON, N1G 2W1 (Canada)Search for more papers by this authorDr. Gale G. Bozzo, Corresponding Author Dr. Gale G. Bozzo [email protected] Department of Plant Agriculture, University of Guelph, 50 Stone Road E., Guelph, ON, N1G 2W1 (Canada)Department of Plant Agriculture, University of Guelph, 50 Stone Road E., Guelph, ON, N1G 2W1 (Canada)Search for more papers by this author Jonathon Roepke, Jonathon Roepke Department of Plant Agriculture, University of Guelph, 50 Stone Road E., Guelph, ON, N1G 2W1 (Canada)Search for more papers by this authorDr. Gale G. Bozzo, Corresponding Author Dr. Gale G. Bozzo [email protected] Department of Plant Agriculture, University of Guelph, 50 Stone Road E., Guelph, ON, N1G 2W1 (Canada)Department of Plant Agriculture, University of Guelph, 50 Stone Road E., Guelph, ON, N1G 2W1 (Canada)Search for more papers by this author First published: 06 November 2013 https://doi.org/10.1002/cbic.201300474Citations: 19Read the full textAboutPDF ToolsRequest permissionExport citationAdd to favoritesTrack citation ShareShare Give accessShare full text accessShare full-text accessPlease review our Terms and Conditions of Use and check box below to share full-text version of article.I have read and accept the Wiley Online Library Terms and Conditions of UseShareable LinkUse the link below to share a full-text version of this article with your friends and colleagues. Learn more.Copy URL Share a linkShare onFacebookTwitterLinkedInRedditWechat Graphical Abstract You are what you eat: Quercetin 3-O-glucoside-7-O-rhamnoside is a rare natural product with potential biological importance. We describe a strategy for the regioselective synthesis of this bisglycoside by feeding quercetin 3-O-glucoside, a naturally abundant precursor, to metabolically engineered Escherichia coli. Citing Literature Supporting Information As a service to our authors and readers, this journal provides supporting information supplied by the authors. Such materials are peer reviewed and may be re-organized for online delivery, but are not copy-edited or typeset. Technical support issues arising from supporting information (other than missing files) should be addressed to the authors. Filename Description cbic_201300474_sm_miscellaneous_information.pdf311.1 KB miscellaneous_information Please note: The publisher is not responsible for the content or functionality of any supporting information supplied by the authors. Any queries (other than missing content) should be directed to the corresponding author for the article. Volume14, Issue18December 16, 2013Pages 2418-2422 RelatedInformation