对乙酰氨基酚
四方晶系
碳纤维
材料科学
化学
组合化学
结晶学
复合材料
晶体结构
生物化学
复合数
作者
Francis Packiaraj Don Disouza,Shen‐Ming Chen,Tse-Wei Chen,Shen‐Ming Chen,Wen-Chin Liou,Bih-Show Lou,Wedad A. Al-onazi,M. Ajmal Ali,Mohamed S. Elshikh
标识
DOI:10.1016/j.jiec.2024.01.052
摘要
Acetaminophen (AAP) is well recognized as a pharmaceutical agent but prolonged consumption of AAP causes serious health issues for human beings. Herein we focus on BiOCl implanted with functionalized carbon nanotube (f-CNT) used to predict AAP levels in the human body samples by electrochemical detection. Bismuth Oxy Chloride (BiOCl) improves electrochemical performance with its electrochemical active sites, it suffers from sluggish kinetics with electron transfer. The composites of BiOCl and f-CNT are well-dispersed substantially, and the synergistic interface between BiOCl and f-CNT improves the electron transfer properties, alongside the catalytic activity enhanced with the large surface area of f-CNT. Notably, the BiOCl/f-CNT/Glassy carbon electrode (GCE) composite exhibits an excellent redox AAP detection in the electrochemical methods of cyclic voltammetry and different pulse voltammetry in pH-7.0 phosphate buffer solution at 0.4 V. The BiOCl/f-CNT composite achieves an outstanding lower detection limit of 0.0016 µM with a wide linear range of 0.01 to 650 µM of AAP with a higher sensitivity of 0.8754 µA µM-1 cm-2. Moreover, composite additionally depicts good selectivity and outstanding repeatability, reproducibility, and strong stability. However, human urine and blood serum gain insights into the clinical detection of AAP with an Acceptable recovery range.
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