药物输送
生化工程
纳米技术
药品
化学
风险分析(工程)
材料科学
医学
药理学
工程类
作者
Rokeya Sultana,Sourav Mohanto,Adrija Bhunia,Aritra Biswas,Mohammad Shabib Akhtar,Vijay Mishra,Dimple Modi,Alaa A. A. Aljabali,Murtaza M. Tambuwala,Md. Faiyazuddin
出处
期刊:Current Drug Delivery
[Bentham Science]
日期:2024-02-22
卷期号:21
被引量:2
标识
DOI:10.2174/0115672018287719240214075810
摘要
Abstract: The utilization of novel drug delivery systems loaded with essential oils has gained significant attention as a promising approach for biomedical applications in recent years. Plants possess essential oils that exhibit various medicinal properties, i.e., anti-oxidant, anti-microbial, anti- inflammatory, anti-cancer, immunomodulatory, etc., due to the presence of various phytoconstituents, including terpenes, phenols, aldehydes, ketones, alcohols, and esters. An understanding of conventional and advanced extraction techniques of Essential Oils (EOs) from several plant sources is further required before considering or loading EOs into drug delivery systems. Therefore, this article summarizes the various extraction techniques of EOs and their existing limitations. The in-built biological applications of EOs are of prerequisite importance for treating several diseases. Thus, the mechanisms of action of EOs for anti-inflammatory, anti-oxidant, anti-bacterial activities, etc., have been further explored in this article. The encapsulation of essential oils in micro or nanometric systems is an intriguing technique to render adequate stability to the thermosensitive compounds and shield them against environmental factors that might cause chemical degradation. Thus, the article further summarizes the advanced drug delivery approaches loaded with EOs and current challenges in the future outlook of EOs for biomedical applications.
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