Brief Reviews: Magnesium in Heart Muscle

HomeCirculation ResearchVol. 33, No. 4Brief Reviews: Magnesium in Heart Muscle Free AccessResearch ArticlePDF/EPUBAboutView PDFSections ToolsAdd to favoritesDownload citationsTrack citationsPermissions ShareShare onFacebookTwitterLinked InMendeleyReddit Jump toFree AccessResearch ArticlePDF/EPUBBrief Reviews: Magnesium in Heart Muscle PHILIP I. POLIMENI and ERNEST PAGE PHILIP I. POLIMENIPHILIP I. POLIMENI Departments of Medicine and Physiology, Pritzker School of Medicine, The University of Chicago, Chicago, Illinois 60637 Search for more papers by this author and ERNEST PAGEERNEST PAGE Departments of Medicine and Physiology, Pritzker School of Medicine, The University of Chicago, Chicago, Illinois 60637 Search for more papers by this author Originally published1 Oct 1973https://doi.org/10.1161/01.RES.33.4.367Circulation Research. 1973;33:367–374 Previous Back to top Next FiguresReferencesRelatedDetailsCited By Shi X, Huang L, Lilley D, Harbury P and Herschlag D (2016) The solution structural ensembles of RNA kink-turn motifs and their protein complexes, Nature Chemical Biology, 10.1038/nchembio.1997, 12:3, (146-152), Online publication date: 1-Mar-2016. Švagždienė M, Širvinskas E, Baranauskienė D and Adukauskienė D (2015) Correlation of magnesium deficiency with C-reactive protein in elective cardiac surgery with cardiopulmonary bypass for ischemic heart disease, Medicina, 10.1016/j.medici.2015.03.003, 51:2, (100-106), . Jahnen-Dechent W and Ketteler M (2012) Magnesium basics, Clinical Kidney Journal, 10.1093/ndtplus/sfr163, 5:Suppl 1, (i3-i14), Online publication date: 1-Feb-2012. Watanabe M, Shinohara A, Matsukawa T, Chiba M, Wu J, Iesaki T and Okada T (2011) Chronic magnesium deficiency decreases tolerance to hypoxia/reoxygenation injury in mouse heart, Life Sciences, 10.1016/j.lfs.2011.01.027, 88:15-16, (658-663), Online publication date: 1-Apr-2011. Kim S, Kang H, Kang M, Yu X, Park S, Kim I, Kim N, Kim S, Kwak Y and Kim J (2005) α1-Agonists-induced Mg2+ efflux is related to MAP kinase activation in the heart, Biochemical and Biophysical Research Communications, 10.1016/j.bbrc.2005.06.022, 333:4, (1132-1138), Online publication date: 1-Aug-2005. Fagan T and Romani A (2001) α 1 -Adrenoceptor-induced Mg 2+ extrusion from rat hepatocytes occurs via Na + -dependent transport mechanism , American Journal of Physiology-Gastrointestinal and Liver Physiology, 10.1152/ajpgi.2001.280.6.G1145, 280:6, (G1145-G1156), Online publication date: 1-Jun-2001. Okorodudu A, Yang H and Tarek Elghetany M (2001) Ionized magnesium in the homeostasis of cells: intracellular threshold for Mg2+ in human platelets, Clinica Chimica Acta, 10.1016/S0009-8981(00)00387-9, 303:1-2, (147-154), Online publication date: 1-Jan-2001. Raghu C, Peddeswara Rao P and Seshagiri Rao D (1999) Protective effect of intravenous magnesium in acute myocardial infarction following thrombolytic therapy, International Journal of Cardiology, 10.1016/S0167-5273(99)00125-4, 71:3, (209-215), Online publication date: 1-Dec-1999. Parikka H, Toivonen L, Verkkala K, Järvinen A and Nieminen M (2011) Ventricular arrhythmia suppression by magnesium treatment after coronary artery bypass surgery, International Journal of Angiology, 10.1007/BF01616447, 8:03, (165-170) Bernard M, Caus T, Sciaky M, Lan C and Cozzone P (1999) Optimized cardiac graft preservation: a comparative experimental study using P-31 magnetic resonance spectroscopy and biochemical analyses, The Journal of Heart and Lung Transplantation, 10.1016/S1053-2498(98)00046-1, 18:6, (572-581), Online publication date: 1-Jun-1999. LaFleur D, Chiang J, Fagin J, Schwartz S, Shah P, Wallner K, Forrester J and Sharifi B (1997) Aortic Smooth Muscle Cells Interact with Tenascin-C through Its Fibrinogen-like Domain, Journal of Biological Chemistry, 10.1074/jbc.272.52.32798, 272:52, (32798-32803), Online publication date: 1-Dec-1997. Reinhart R (1996) Serum and erythrocyte magnesium in critically ill patients?, Intensive Care Medicine, 10.1007/BF01709511, 22:8, (722-723), Online publication date: 1-Aug-1996. Shechter M, Hod H, Chouraqui P, Kaplinsky E and Rabinowitz B (1995) Magnesium therapy in acute myocardial infarction when patients are not candidates for thrombolytic therapy, The American Journal of Cardiology, 10.1016/S0002-9149(99)80546-3, 75:5, (321-323), Online publication date: 1-Feb-1995. Jynge P, Blankson H, Falck G, Refsum H, Karlsson J, Almén T and Øksendal A (2016) Sodium-Calcium Relationships and Cardiac Function during Coronary Bolus Perfusion, Acta Radiologica, 10.1177/0284185195036S39915, 36:399_suppl, (122-134), Online publication date: 1-Jan-1995. Shirey T (1995) Critical care profile testing for informed treatment of severely ill patients, RBM-News, 10.1016/0222-0776(96)89506-X, 17:7, (173-181), Online publication date: 1-Jan-1995. Romani A, Marfella C and Scarpa A (1995) Mg2+ Homeostasis in cardiac ventricular myocytes Biochemistry of Cell Membranes, 10.1007/978-3-0348-9057-1_16, (231-244), . Caspi J, Coles J, Benson L, Herman S, Augustine J and Wilson G (1994) Dose-related effects of magnesium on myocardial function in the neonate., Hypertension, 23:2, (174-178), Online publication date: 1-Feb-1994. Takemoto N, Kuroda H, Hamasaki T, Hara Y, Ishiguro S and Mori T (1994) Effect of magnesium and calcium on myocafdial protection by cardioplegic solutions, The Annals of Thoracic Surgery, 10.1016/0003-4975(94)90389-1, 57:1, (177-182), Online publication date: 1-Jan-1994. Stringham J, Paulsen K, Southard J, Mentzer R and Belzer F (1994) Forty-hour preservation of the rabbit heart: Optimal osmolarity, [Mg2+], and pH of a modified UW solution, The Annals of Thoracic Surgery, 10.1016/0003-4975(94)91062-6, 58:1, (7-13), Online publication date: 1-Jul-1994. Gottlieb S (1994) Diuretics Congestive Heart Failure, 10.1007/978-1-4613-8315-4_21, (341-353), . Rabkin S, Freestone N and Quamme G (1994) Nifedipine does not alter the increased cystolic free magnesium during inhibition of mitochondrial function in isolated cardiac myocytes, General Pharmacology: The Vascular System, 10.1016/0306-3623(94)90178-3, 25:7, (1483-1491), Online publication date: 1-Nov-1994. Bianchi C and Liu D (1993) Calcium dependent magnesium uptake in myocardium, Life Sciences, 10.1016/0024-3205(93)90105-C, 52:14, (1225-1229), Online publication date: 1-Jan-1993. Olbrich H, Michaelis H, Vandeplassche G, Borgers M, Oremek G, Krause E, Satter P, Kober G, Mutschler E and Kaltenbach M (1993) Ultrastructural calcium distribution and myocardial calcium content in human idiopathic dilated cardiomyopathy, Cardiovascular Pathology, 10.1016/1054-8807(93)90024-V, 2:2, (127-136), Online publication date: 1-Apr-1993. Gullestad L, Birkeland K, Vanberg P, Mølstad P, Høyer M and Kjekshus J (1993) The effect of magnesium versus verapamil on supraventricular arrhythmias, Clinical Cardiology, 10.1002/clc.4960160512, 16:5, (429-434), Online publication date: 1-May-1993. Horner S (1992) Efficacy of intravenous magnesium in acute myocardial infarction in reducing arrhythmias and mortality. Meta-analysis of magnesium in acute myocardial infarction., Circulation, 86:3, (774-779), Online publication date: 1-Sep-1992. Romani A and Scarpa A (1992) Regulation of cell magnesium, Archives of Biochemistry and Biophysics, 10.1016/0003-9861(92)90086-C, 298:1, (1-12), Online publication date: 1-Oct-1992. Millane T, Ward D and Camm A (1992) Is hypomagnesemia arrhythmogenic?, Clinical Cardiology, 10.1002/clc.4960150210, 15:2, (103-108), Online publication date: 1-Feb-1992. Reinhart R (1992) Magnesium deficiency: Recognition and treatment in the emergency medicine setting, The American Journal of Emergency Medicine, 10.1016/0735-6757(92)90133-I, 10:1, (78-83), Online publication date: 1-Jan-1992. Mallet R, Kang Y, Mukohara N and Bünger R (1992) Use of cytosolic metabolite patterns to estimate free magnesium in normoxic myocardium, Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease, 10.1016/0925-4439(92)90140-I, 1139:3, (239-247), Online publication date: 1-Jul-1992. Saeki Y, Kawai M and Zhao Y (1991) Comparison of crossbridge dynamics between intact and skinned myocardium from ferret right ventricles., Circulation Research, 68:3, (772-781), Online publication date: 1-Mar-1991. Kristensen S and Hørder M (2018) The influence of extracellular magnesium on cell damage induced by ATP depletion in human fibroblasts, Scandinavian Journal of Clinical and Laboratory Investigation, 10.1080/00365513.1991.11978683, 51:1, (11-15), Online publication date: 1-Jan-1991. Reinhart R, Marx J, Broste S and Haas R (1991) Myocardial magnesium: Relation to laboratory and clinical variables in patients undergoing cardiac surgery, Journal of the American College of Cardiology, 10.1016/S0735-1097(10)80179-2, 17:3, (651-656), Online publication date: 1-Mar-1991. Craddock L, Miller B, Clifton G, Krumbach B and Pluss W (1991) Resuscitation from prolonged cardiac arrest with high-dose intravenous magnesium sulfate, The Journal of Emergency Medicine, 10.1016/0736-4679(91)90220-A, 9:6, (469-476), Online publication date: 1-Nov-1991. Kinoshita K, Oe M and Tokunaga K (1991) Superior protective effect of low-calcium, magnesium-free potassium cardioplegic solution on ischemic myocardium, The Journal of Thoracic and Cardiovascular Surgery, 10.1016/S0022-5223(19)36701-7, 101:4, (695-702), Online publication date: 1-Apr-1991. Reinhart R (1991) Clinical correlates of the molecular and cellular actions of magnesium on the cardiovascular system, American Heart Journal, 10.1016/0002-8703(91)90160-J, 121:5, (1513-1521), Online publication date: 1-May-1991. Gottlieb S, Baruch L, Kukin M, Bernstein J, Fisher M and Packer M (1990) Prognostic importance of the serum magnesium concentration in patients with congestive heart failure, Journal of the American College of Cardiology, 10.1016/S0735-1097(10)80329-8, 16:4, (827-831), Online publication date: 1-Oct-1990. Blatter L (1990) Intracellular free magnesium in frog skeletal muscle studied with a new type of magnesium-selective microelectrode: interactions between magnesium and sodium in the regulation of [Mg]i, Pfl�gers Archiv European Journal of Physiology, 10.1007/BF00392059, 416:3, (238-246), Online publication date: 1-May-1990. SJÖGREN A, EDVINSSON L and FALLGREN B (2011) Magnesium deficiency in coronary artery disease and cardiac arrhythmias, Journal of Internal Medicine, 10.1111/j.1365-2796.1989.tb01383.x, 226:4, (213-222), Online publication date: 1-Oct-1989. Reynolds T, Geffin G, Titus J, O'Keefe D and Daggett W (1989) Myocardial preservation related to magnesium content of hyperkalemic cardioplegic solutions at 8 °C, The Annals of Thoracic Surgery, 10.1016/0003-4975(89)90033-7, 47:6, (907-913), Online publication date: 1-Jun-1989. BUNGER R, MALLET R and HARTMAN D (1989) Pyruvate-enhanced phosphorylation potential and inotropism in normoxic and postischemic isolated working heart. Near-complete prevention of reperfusion contractile failure, European Journal of Biochemistry, 10.1111/j.1432-1033.1989.tb14637.x, 180:1, (221-233), Online publication date: 1-Mar-1989. Surawicz B (1989) Is hypomagnesemia or magnesium deficiency arrhythmogenic?, Journal of the American College of Cardiology, 10.1016/0735-1097(89)90494-4, 14:4, (1093-1096), Online publication date: 1-Oct-1989. Schilling W (1988) Effect of divalent cation chelation on dihydropyridine binding in isolated cardiac sarcolemma vesicles, Biochimica et Biophysica Acta (BBA) - Biomembranes, 10.1016/0005-2736(88)90554-8, 943:2, (220-230), Online publication date: 1-Aug-1988. Savabi F, Gura V, Bessman S and Brautbar N (1988) Effects of magnesium depletion on myocardial high-energy phosphates and contractility, Biochemical Medicine and Metabolic Biology, 10.1016/0885-4505(88)90069-2, 39:2, (131-139), Online publication date: 1-Apr-1988. Bünger R, Mallet R and Hartman D (1988) Redox Manipulation of Free Cardiac Adenylates and Purine Nucleoside Release Myocardial Energy Metabolism, 10.1007/978-94-009-1319-6_7, (67-81), . Rasmussen H, Videbaek R, Melchior T, Aurup P, Cintin C and Pedersen N (1988) Myocardial contractility and performance capacity after magnesium infusions in young healthy persons: A double-blind, placebo-controlled, cross-over study, Clinical Cardiology, 10.1002/clc.4960110807, 11:8, (541-545), Online publication date: 1-Aug-1988. Rasmussen H, Suenson M, Mcnair P, Nørregård P and Balslev S (1987) Magnesium infusion reduces the incidence of arrhythmias in acute myocardial infarction. A double-blind placebo-controlled study, Clinical Cardiology, 10.1002/clc.4960100610, 10:6, (351-356), Online publication date: 1-Jun-1987. Shattock M, Hearse D and Fry C (1987) The ionic basis of the anti-ischemic and anti-arrhythmic properties of magnesium in the heart., Journal of the American College of Nutrition, 10.1080/07315724.1987.10720162, 6:1, (27-33), Online publication date: 1-Feb-1987. Borchgrevink P and Jynge P (1987) Acquired magnesium deficiency and myocardial tolerance to ischemia., Journal of the American College of Nutrition, 10.1080/07315724.1987.10720199, 6:4, (355-363), Online publication date: 1-Aug-1987. Reinhart R, Marx J, Haas R and Desbiens N (1987) Intracellular magnesium of mononuclear cells from venous blood of clinically healthy subjects, Clinica Chimica Acta, 10.1016/0009-8981(87)90371-8, 167:2, (187-195), Online publication date: 1-Aug-1987. BUNGER R and SOBOLL S (1986) Cytosolic adenylates and adenosine release in perfused working heart. Comparison of whole tissue with cytosolic non-aqueous fractionation analyses, European Journal of Biochemistry, 10.1111/j.1432-1033.1986.tb09854.x, 159:1, (203-213), Online publication date: 1-Aug-1986. Zama N and Towns R (1986) Effect of isoproterenol (ISO) on rat heart, liver, kidney, and muscle tissue levels of zinc, copper, and magnesium, Biological Trace Element Research, 10.1007/BF02795617, 10:3, (189-199), Online publication date: 1-Sep-1986. Yano Y, Milam D and Alexander J (1985) Terminal magnesium cardioplegia: Protective effect in the isolated rat heart model using calcium accentuated ischemic damage, Journal of Surgical Research, 10.1016/0022-4804(85)90121-0, 39:6, (529-534), Online publication date: 1-Dec-1985. Blanchard E and Solaro R (1984) Inhibition of the activation and troponin calcium binding of dog cardiac myofibrils by acidic pH., Circulation Research, 55:3, (382-391), Online publication date: 1-Sep-1984. Brown A and Kitchen J (1984) Magnesium Augmentation During Reperfusion for the Reduction of Postischaemic Myocardial Damage Coronary Artery Surgery, 10.1007/978-3-642-69638-1_21, (106-111), . Flatman P (1984) Magnesium transport across cell membranes, The Journal of Membrane Biology, 10.1007/BF01868686, 80:1, (1-14), Online publication date: 1-Feb-1984. Dobson J (1983) Mechanism of adenosine inhibition of catecholamine-induced responses in heart., Circulation Research, 52:2, (151-160), Online publication date: 1-Feb-1983. Dobson J and Fenton R (1983) Antiadrenergic Effects of Adenosine in the Heart Regulatory Function of Adenosine, 10.1007/978-1-4613-3909-0_23, (363-376), . Kalsner S (2012) The effect of magnesium deficiency and excess on bovine coronary artery tone and responses to agonists, British Journal of Pharmacology, 10.1111/j.1476-5381.1983.tb09413.x, 78:4, (629-638), Online publication date: 1-Apr-1983. Holubarsch C, Alpert N, Goulette R and Mulieri L (1982) Heat production during hypoxic contracture of rat myocardium., Circulation Research, 51:6, (777-786), Online publication date: 1-Dec-1982. Wakabayashi A, Nishi T and Guilmette J (1982) Experimental evaluation of magnesium cardioplegia, The Journal of Thoracic and Cardiovascular Surgery, 10.1016/S0022-5223(19)38957-3, 84:5, (685-688), Online publication date: 1-Nov-1982. Madden J, Smith G and Llaurado J (1982) Myocardial K kinetics in rats on Mg-deficient diet., Journal of the American College of Nutrition, 10.1080/07315724.1982.10719002, 1:4, (323-329), Online publication date: 1-Jan-1982. Rupp H (1982) Calcium-Dependent Activation of Cardiac Myofibrils Advances in Myocardiology, 10.1007/978-1-4899-5561-6_44, (455-466), . Vetter R and Saks V (1981) THE CREATINE PHOSPHOKINASE SYSTEM — A FURTHER TARGET OF CALCIUM IONS IN HEART MUSCLE CELLS? Cardiovascular Physiology: Heart, Peripheral Circulation and Methodology, 10.1016/B978-0-08-026820-0.50022-6, (159-166), . Waser P and Schaub M (1981) Effects of Cardiac Glycosides on Myofibrils Cardiac Glycosides, 10.1007/978-3-642-68163-9_19, (437-457), . Wu S, Pieper G, Salhany J and Eliot R (2002) Measurement of free magnesium in perfused and ischemic arrested heart muscle. A quantitative phosphorus-31 NMR and multiequilibrium analysis, Biochemistry, 10.1021/bi00529a012, 20:26, (7399-7403), Online publication date: 1-Dec-1981. Burt C (1981) Nuclear Magnetic Resonance Studies of Muscle Constituents in Living Tissue Cell and Muscle Motility, 10.1007/978-1-4684-8196-9_10, (375-398), . Khatter J, Soni P, Hoeschen R, Alto L and Dhalla N (1981) Subcellular Effects of Taurine on Guinea Pig Heart The Effects of Taurine on Excitable Tissues, 10.1007/978-94-009-8093-8_21, (281-293), . Bigg R and Chia R (1981) MAGNESIUM DEFICIENCY: ROLE IN ARRHYTHMIAS COMPLICATING ACUTE MYOCARDIAL INFARCTION?, Medical Journal of Australia, 10.5694/j.1326-5377.1981.tb135627.x, 1:7, (346-348), Online publication date: 1-Apr-1981. Stephenson E (1981) Activation of fast skeletal muscle: contributions of studies on skinned fibers, American Journal of Physiology-Cell Physiology, 10.1152/ajpcell.1981.240.1.C1, 240:1, (C1-C19), Online publication date: 1-Jan-1981. Krasner B, Girdwood R and Smith H (1981) The effect of slow releasing oral magnesium chloride on the qtc interval of the electrocardiogram during open heart surgery, Canadian Anaesthetists’ Society Journal, 10.1007/BF03007798, 28:4, (329-333), Online publication date: 1-Jul-1981. Marban E, Rink T, Tsien R and Tsien R (1980) Free calcium in heart muscle at rest and during contraction measured with Ca2+-sensitive microelectrodes, Nature, 10.1038/286845a0, 286:5776, (845-850), Online publication date: 1-Aug-1980. Rupp H (1980) Modulation of tension generation at the myofibrillar level—an analysis of the effect of magnesium adenosine triphosphate, magnesium, pH, sarcomere length and state of phosphorylationDie Modulation der Spannungsentwicklung auf der Ebene der Myofibrillen—Wirkung von Magnesium-Adenosintriphosphat, Magnesium, pH, Sarkomerenlänge und Grad der Phosphorylierung, Basic Research in Cardiology, 10.1007/BF01907579, 75:2, (295-317), Online publication date: 1-Mar-1980. Maughan D, Low E, Litten R, Brayden J and Alpert N (1979) Calcium-activated muscle from hypertrophied rabbit hearts. Mechanical and correlated biochemical changes., Circulation Research, 44:2, (279-287), Online publication date: 1-Feb-1979. Jefferson L, Flaim K and Morgan H (1979) PEPTIDE-CHAIN INITIATION IN HEART AND SKELETAL MUSCLE Modulation of Protein Function, 10.1016/B978-0-12-066250-0.50027-2, (369-389), . Kopp S and Barany M (1979) Phosphorylation of the 19,000-dalton light chain of myosin in perfused rat heart under the influence of negative and positive inotropic agents., Journal of Biological Chemistry, 10.1016/S0021-9258(19)86419-0, 254:23, (12007-12012), Online publication date: 1-Dec-1979. Wnuk W, Cox J, Kohler L and Stein E (1979) Calcium- and magnesium-binding properties of a high affinity calcium-binding protein from crayfish sarcoplasm., Journal of Biological Chemistry, 10.1016/S0021-9258(18)50592-5, 254:12, (5284-5289), Online publication date: 1-Jun-1979. Kahles H, Gebhard M, Mezger V, Nordbeck H, Preuße C and Spieckermann P (1979) The role of ATP and lactic acid for mitochondrial function during myocardial ischemiaDie Bedeutung von ATP und Milchsäure für die Mitochondrienfunktion während einer Myokardischämie, Basic Research in Cardiology, 10.1007/BF01907503, 74:6, (611-620), Online publication date: 1-Nov-1979. Watterson J, Kohler L and Schaub M (1979) Evidence for two distinct affinities in the binding of divalent metal ions to myosin., Journal of Biological Chemistry, 10.1016/S0021-9258(18)50391-4, 254:14, (6470-6477), Online publication date: 1-Jul-1979. Allen D and Blinks J (1978) Calcium transients in aequorin-injected frog cardiac muscle, Nature, 10.1038/273509a0, 273:5663, (509-513), Online publication date: 1-Jun-1978. Hearse D, Stewart D and Braimbridge M (1978) Myocardial protection during ischemic cardiac arrest, The Journal of Thoracic and Cardiovascular Surgery, 10.1016/S0022-5223(19)39603-5, 75:6, (877-885), Online publication date: 1-Jun-1978. Bolitho Donaldson S, Hermansen L and Bolles L (1978) Differential, direct effects of H+ on Ca2+-activated force of Skinned fibers from the soleus, cardiac and adductor magnus muscles of rabbits, Pfl�gers Archiv European Journal of Physiology, 10.1007/BF00585248, 376:1, (55-65), . Paradise N, Beeler G and Visscher M (1978) Magnesium net fluxes and distribution in rabbit myocardium in irreversible contracture, American Journal of Physiology-Cell Physiology, 10.1152/ajpcell.1978.234.3.C115, 234:3, (C115-C121), Online publication date: 1-Mar-1978. Levine B, Thornton J, Fernandes R, Kelly C and Mercola D (1978) Comparison of the calcium- and magnesium-induced structural changes of troponin-C, Biochimica et Biophysica Acta (BBA) - Protein Structure, 10.1016/0005-2795(78)90028-4, 535:1, (11-24), Online publication date: 1-Jul-1978. Vial C, Otokore A, Goldschmidt D and Gautheron D (1978) Studies on the energy-linked Ca2+ accumulation in pig heart mitochondria — Role of Mg2+ ions, Biochimie, 10.1016/S0300-9084(78)80749-4, 60:2, (159-169), Online publication date: 1-May-1978. Chipperfield B and Chipperfield J (1977) Magnesium and the heart, American Heart Journal, 10.1016/S0002-8703(77)80061-6, 93:6, (679-682), Online publication date: 1-Jun-1977. Burtnick L and Kay C (2001) The calcium-binding properties of bovine cardiac troponin C, FEBS Letters, 10.1016/0014-5793(77)80063-X, 75:1-2, (105-110), Online publication date: 15-Mar-1977. Isenberg G (1977) Cardiac Purkinje fibres, Pfl�gers Archiv European Journal of Physiology, 10.1007/BF00580775, 371:1-2, (77-85), . Briggs N, Shiner J, Gleason N, Bruni F and Solaro J (1977) Calcium Binding and Cardiac Myofibril Activation Myocardial Failure, 10.1007/978-3-642-46352-5_10, (80-89), . Rannels D, McKee E and Morgan H (1977) Regulation of Protein Synthesis and Degradation in Heart and Skeletal Muscle Biochemical Actions of Hormones, 10.1016/B978-0-12-452804-8.50011-8, (135-195), . Solaro R and Shiner J (1976) Modulation of Ca2+ control of dog and rabbit cardiac myofibrils by Mg2+. Comparison with rabbit skeletal myofibrils., Circulation Research, 39:1, (8-14), Online publication date: 1-Jul-1976. Potter J, Seidel J, Leavis P, Lehrer S and Gergely J (1976) Effect of Ca2+ binding on troponin C. Changes in spin label mobility, extrinsic fluorescence, and sulfhydryl reactivity., Journal of Biological Chemistry, 10.1016/S0021-9258(17)32886-7, 251:23, (7551-7556), Online publication date: 1-Dec-1976. Diederich K, Lander B and Djonlagic H (1976) Tierexperimentelle Untersuchungen zur Frage einer kaliumabhängigen Modifikation der LidocainwirkungPotassium-dependent modification of the lidocaine effect: An experimental investigation, Basic Research in Cardiology, 10.1007/BF01907786, 71:1, (87-95), Online publication date: 1-Jan-1976. Potter J and Gergely J (1975) The calcium and magnesium binding sites on troponin and their role in the regulation of myofibrillar adenosine triphosphatase., Journal of Biological Chemistry, 10.1016/S0021-9258(19)41347-1, 250:12, (4628-4633), Online publication date: 1-Jun-1975. Vierling W and Reiter M (1975) Frequency-force relationship in guinea-pig ventricular myocardium as influenced by magnesium, Naunyn-Schmiedeberg's Archives of Pharmacology, 10.1007/BF00501299, 289:2, (111-125), . SAKS V, CHERNOUSOVA G, GUKOVSKY D, SMIRNOV V and CHAZOV E (1975) Studies of Energy Transport in Heart Cells. Mitochondrial Isoenzyme of Creatine Phosphokinase: Kinetic Properties and Regulatory Action of Mg2+ Ions, European Journal of Biochemistry, 10.1111/j.1432-1033.1975.tb02299.x, 57:1, (273-290), Online publication date: 1-Sep-1975. Kerrick W and Donaldson S (1975) The comparative effects of [Ca2+] and [Mg2+] on tension generation in the fibers of skinned frog skeletal muscle and mechanically disrupted rat ventricular cardiac muscle, Pfl�gers Archiv European Journal of Physiology, 10.1007/BF00587216, 358:3, (195-201), . Krokhicheva P, Shornikov D and Savelyev M (2019) Development of the technology of obtaining the composite based on the “magnesium-bone substance” for biodegradable implants by the method of powder metallurgy, IOP Conference Series: Materials Science and Engineering, 10.1088/1757-899X/525/1/012029, 525, (012029) October 1, 1973Vol 33, Issue 4 Advertisement Article InformationMetrics © 1973 American Heart Association, Inc.https://doi.org/10.1161/01.RES.33.4.367 Originally publishedOctober 1, 1973 PDF download Advertisement