Childhood atopic eczema consensus document.

3conducted among Xhosa children demonstrated a point prevalence (dermatologist-diagnosed) of 0.7%, 1.1% and 3.7% in rural, peri-urban and urban settings respectively. AE is therefore very rare in Xhosa children in rural settlements and a clear urban/rural gradient exists for the occurrence of AE in black children. AE is frequently undertreated despite severely affecting the quality of life of patients and their families. AE also commonly predates the development of allergic rhinitis and asthma.