The clinical outcome of the endoscopic submucosal dissection of colonic polyps larger than 20 mm. A single medical study.

The aim of this study was to evaluate the safety and efficacy of endoscopic submucosal dissection (ESD) of colonic polyps larger than 20 mm.Between March 2017 and July 2019, a gastro-entero endoscopist team resected 24 large colorectal polyps measuring 20-35 mm in diameter using the ESD technique. After the injection of a mixture of hydroxypropyl methylcellulose with dilute epinephrine and methylene blue into the submucosal layer, a circumferential incision was performed using an electrosurgical knife.A total of 24 colorectal polyps (≥20 mm) from 20 patients were evaluated. The mean age of the patients was 60 years; 16 patients were men and 4 patients were women. The mean polyp size removed by colorectal ESD was 35.3 mm (range 20.0-70.1 mm), and all 24 polyps were larger than 2 cm (100%). There were no cases of delayed bleeding after the colorectal ESD nor were there any post-surgery complications.This study demonstrates the efficacy and safety of carrying out ESD of large polyps. This is important because there is not a large body of literature on this subject in this specific population.Colonic polyps, Endoscopic submucosal dissection, Gastrointestinal endoscopy.Lo scopo di questo studio era di valutare la sicurezza e l’efficacia della dissezione sottomucosa endoscopica (ESD) di polipi del colon di dimensioni maggiori di 20 mm. Tra marzo 2017 e luglio 2019, un team di gastro-entero endoscopisti ha resecato 24 grandi polipi colorettali di 20-35 mm di diametro utilizzando la tecnica ESD. Dopo l’iniezione di una miscela di idrossipropilmetilcellulosa con epinefrina diluita e blu di metilene nello strato sottomucoso, stata eseguita un’incisione circonferenziale utilizzando un elettrobisturi. L’et media dei pazienti era di 60 anni; 16 pazienti erano uomini e 4 pazienti erano donne. La dimensione media del polipo rimosso dall’ESD colorettale era di 35,3 mm (intervallo 20,0-70,1 mm) e tutti i 24 polipi erano pi grandi di 2 cm (100%). Non ci sono stati casi di sanguinamento ritardato dopo ESD colorettale n complicazioni post-chirurgiche. In cnclusione Questo studio dimostra l’efficacia e la sicurezza dell’esecuzione di ESD di grandi polipi. Questo importante perch non c’ una grande quantit di letteratura su questo argomento in questa specifica popolazione.