医学
克罗恩病
随机对照试验
克罗恩病
内科学
疾病
作者
William J. Sandborn,Brian G. Feagan,Edward V. Loftus,Laurent Peyrin‐Biroulet,Gert Van Assche,Geert D’Haens,Stefan Schreiber,Jean‐Frédéric Colombel,James D. Lewis,Subrata Ghosh,Alessandro Armuzzi,Ellen Scherl,Hans Herfarth,L.M. Vitale,Mohamed‐Eslam F. Mohamed,Ahmed A. Othman,Qian Zhou,Bidan Huang,Roopal Thakkar,Aileen L. Pangan
出处
期刊：Gastroenterology
[Elsevier BV]
日期：2020-02-08
卷期号：158 (8): 2123-2138.e8
被引量：303
标识
DOI：10.1053/j.gastro.2020.01.047
摘要
In a phase 2 trial of patients with CD, upadacitinib induced endoscopic remission in a significant proportion of patients compared with placebo. Upadacitinib's benefit/risk profile supports further development for treatment of CD. (Clinicaltrials.gov, Number: NCT02365649).
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