溶解循环
生物
大肠杆菌
溶原循环
噬菌体
基因组
基因
DNA
多重耐药
遗传学
微生物学
病毒
抗药性
作者
Ana Carolina Maganha de Almeida Kumlien,Clara Pérez-Vega,Edgar González-Villalobos,Carles M. Borrego,José Luís Balcázar
出处
期刊:Virus Research
[Elsevier]
日期:2022-01-01
卷期号:307: 198623-198623
被引量:5
标识
DOI:10.1016/j.virusres.2021.198623
摘要
In this study, we present the complete, annotated genome of a new member of the Tequatrovirus (T4-like) genus, Escherichia phage vB_EcoM_C2-3. This phage has an isometric head (92 nm in diameter) and a contractile tail (114 nm in length). Its genome consists of a linear, double-stranded DNA of 167,069bp with an average G+C content of 35.3%. There are 267 predicted genes, of which 125 encode functional proteins, including those for DNA replication, transcription and packaging, phage morphogenesis and cell lysis. Neither genes involved in the regulation of lysogeny nor antibiotic resistance genes were identified. Based on our results, its genomic features provide valuable insights into the use of a potential biocontrol agent, as Escherichia phage vB_EcoM_C2-3 exhibited lytic activity against E. coli, including multidrug-resistant strains.
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