医学
刺激
头颈部癌
唾液腺
周围神经刺激
放射治疗
外科
内科学
作者
Fatemeh Salimi,J Edward Fitzgerald,Stuart S. Winter,Francisco Saavedra,Brian T. Andrews
标识
DOI:10.1016/j.neurom.2022.08.212
摘要
Head and neck cancers represent the sixth most common cancer worldwide with approximately 630,000 new patients diagnosed annually1. Over that decade there has been a 20% increase in the incidence of HNC in the UK and worldwide. Up to 80% of patients will receive radiotherapy as part of their care2,3,4. Dry mouth (xerostomia) remains one of the most significant long-term effects on quality of life following radiotherapy5,6,7. The aim of the project is to develop a bespoke solution combing targeted optimal stimulation of the salivary glands, with minimal discomfort. The proposed system will incorporate a novel stimulating electrode, developed using COMSOL simulation, featuring focused activation with increased depth penetration and minimal discomfort.
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