Maturity-onset diabetes of the young type 7 (MODY7) and mutation in the Krüppel-like transcription factor 11 (KLF11) gene

Learning points for cliniciansThis report identified a novel missense Krüppel-like transcription factor 11 (KLF11) variant in a family in which two patients were diagnosed with diabetes mellitus, while one patient had hyperinsulinemia.This report highlights molecular diagnosis of maturity-onset diabetes of the young (MODY) is crucial for effectively treating, predicting outcomes, and providing genetic counseling for individuals with monogenic diabetes.MODY7 patients may benefit from the administration of oral antidiabetic drugs, subcutaneous insulin injections, and dietary intervention.