Photoredox Radical‐Polar Crossover Reaction of gem‐Difluoroalkenes: A Facile Access to Diverse Difluoroalkyl Sulfides

Difluoroalkyl sulfide (‐CF2S‐) moieties are an important class of skeletons in medicinal chemistry. Herein, a photoredox radical‐polar crossover reaction is reported for the three‐component thiofluorination, thiohydroxylation, thioalkoxylation, thioaminolation, and thiochlorination of gem‐difluoroalkenes towards diverse α‐functionalized difluoroalkyl sulfides. Such an approach features mild conditions, operational simplicity, and good substrate scope.