Study on chemical constituents of Trollius ledebouri

OBJECTIVE To study the chemical constituents from the flower of Trollius ledebouri. METHODS The components were separated by means of solvent extraction, repeated chromatography with silica column and Sephadex LH-20. The structures were determined by spectral analysis. RESULTS Fourteen compounds were isolated as palmitic acid(Ⅰ) , tetracosene(Ⅱ),β-sitosterol(Ⅲ), salvigenin(Ⅳ) , veratric acid(Ⅴ), vanillic acid(Ⅵ) , scrophulein(Ⅶ), daucosterol(Ⅷ), methyl P-hydroxybenzoate(Ⅸ),chrysoeriol(Ⅹ) ,4-hydroxyben-zoic acid(Ⅺ), luteolin(Ⅺ) , quercetin(ⅩⅢ)and tilianin(ⅩⅣ). CONCLUSION All compounds except Ⅰ, Ⅲ , and Ⅴ were isolated from the genus Trollius for the first time.