Health Behaviors and Neurocognitive Function in Survivors of Childhood Cancer

Article Tools REVIEW ARTICLES Neurocognitive Outcomes in Survivors of Pediatric Cancer Article Tools OPTIONS & TOOLS Export Citation Track Citation Add To Favorites Rights & Permissions COMPANION ARTICLES No companion articles ARTICLE CITATION DOI: 10.1200/JCO.20.02512 Journal of Clinical Oncology - published online before print April 22, 2021 PMID: 33886366 Health Behaviors and Neurocognitive Function in Survivors of Childhood Cancer Alicia S. Kunin-Batson, PhD1xAlicia S. Kunin-BatsonSearch for articles by this author; James L. Klosky , PhD2xJames L. KloskySearch for articles by this author; Bonnie Carlson-Green , PhD3xBonnie Carlson-GreenSearch for articles by this author; and Tara M. Brinkman , PhD4xTara M. BrinkmanSearch for articles by this author Show More 1Department of Pediatrics, University of Minnesota Medical School, Minneapolis, MN2Department of Pediatrics, Emory University School of Medicine & Aflac Cancer and Blood Disorders Center, Children's Healthcare of Atlanta, Atlanta, GA3Psychological Services, Children's Minnesota, Minneapolis, MN4Departments of Epidemiology & Cancer Control and Psychology, St. Jude Children's Research Hospital https://doi.org/10.1200/JCO.20.02512 First Page Full Text PDF Figures and Tables © 2021 by American Society of Clinical OncologyCONTEXT SUMMARYKey ObjectiveTo examine current research linking survivors' health behaviors and neurocognitive functioning to inform clinical and research programming. Although previous reviews have summarized the importance of lifestyle behaviors to childhood cancer survivors' health, none have focused on associations with neurocognitive outcomes.Knowledge GeneratedLiterature examining the impact of key health behaviors on neurocognitive functioning is reviewed. Proposed mechanisms for how these behaviors affect neurocognitive outcomes are offered, and health behavior interventions that have measured neurocognitive outcomes among childhood cancer survivors are described.RelevanceHealth behaviors should be leveraged as potential clinical intervention targets in survivors with neurocognitive dysfunction.AUTHOR CONTRIBUTIONSConception and design: All authorsManuscript writing: All authorsFinal approval of manuscript: All authorsAccountable for all aspects of the work: All authorsAUTHORS' DISCLOSURES OF POTENTIAL CONFLICTS OF INTERESTHealth Behaviors and Neurocognitive Function in Survivors of Childhood CancerThe following represents disclosure information provided by authors of this manuscript. All relationships are considered compensated unless otherwise noted. Relationships are self-held unless noted. I = Immediate Family Member, Inst = My Institution. Relationships may not relate to the subject matter of this manuscript. For more information about ASCO's conflict of interest policy, please refer to www.asco.org/rwc or ascopubs.org/jco/authors/author-center.Open Payments is a public database containing information reported by companies about payments made to US-licensed physicians (Open Payments).James L. KloskyEmployment: InTown Physical TherapyResearch Funding: Merck Sharp and DohmeNo other potential conflicts of interest were reported.