内根鞘
毛囊
内卷(密宗)
头发周期
角蛋白
生物
毛乳头
毛囊
细胞生物学
牙囊
免疫组织化学
外根鞘
解剖
病理
内分泌学
干细胞
免疫学
医学
神经科学
古生物学
意识
标识
DOI:10.1046/j.1365-2133.1997.17641854.x
摘要
The transition from the growth phase (anagen) to the involution phase (catagen) involves profound morphological changes in the human hair follicle. Club hair and epithelial column formation, for example, are key features of the catagen phase, which result in the disruption of physical interaction between the bulb and the dermal papilla. However, the dynamics and tissue remodelling that occur during this involution process remain largely unknown. Using monoclonal antibodies directed against K14 keratin, trichohyalin, transglutaminase I, desmoglein and Ki67 antigen, we followed the movements of each of the main hair follicle compartments during the onset of catagen. Our results indicate that the inner root sheath is an early target in this process, suggesting a key role for this compartment in the maintenance of hair follicle homeostasis.
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