Potential Efficacy of Herbal Medicine-Derived Carbon Dots in the Treatment of Diseases: From Mechanism to Clinic

纳米技术 纳米材料 机制(生物学) 药物输送 碳纤维 医学 材料科学 复合数 哲学 认识论 复合材料
作者
Mingtang Zeng,Yao Wang,Maozhu Liu,Yuxun Wei,Jie Wen,Yu-Chen Zhang,Tao Chen,Nianyu He,Ping Fan,Xinhua Dai
出处
期刊:International Journal of Nanomedicine [Dove Medical Press]
卷期号:Volume 18: 6503-6525 被引量:7
标识
DOI:10.2147/ijn.s431061
摘要

Abstract: Carbon dots (CDs), a crucial component of nanomaterials, are zero-dimensional nanomaterials with carbon as the backbone structure and smaller than 10 nm. Due to their beneficial characteristics, they are widely used in biomedical fields such as biosensors, drug delivery, bio-imaging, and interactions with DNA. Interestingly, a novel type of carbon dot, generated by using herbal medicines as synthetic raw materials, has emerged as the most recent incomer in the family of CDs with the extensive growth in the number of materials selected for carbon dots synthesis. Herbal medicine-derived carbon dots (HM-CDs) have been employed in the biomedical industry, and are rapidly emerging as "modern nanomaterials" due to their unique structures and exceptional capabilities. Emerging trends suggest that their specific properties can be used in bleeding disorders, gastrointestinal disorders, inflammation-related diseases, and other common intractable diseases including cancer, menopausal syndrome, central nervous system disorders, and pain of various forms and causes. In addition, HM-CDs have been found to have organ-protective and antioxidant properties, as evidenced by extensive studies. This research provides a more comprehensive understanding of the biomedical applications of HM-CDs for the aforementioned disorders and investigates the intrinsic pharmacological activities and mechanisms of these HM-CDs to further advance their clinical applications. Keywords: herbal medicine, carbon dots, disease treatment, nanomaterials, potential mechanism
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