The relationship between sedentary behavior and dry eye disease

医学 优势比 久坐行为 逻辑回归 人口统计学的 队列 人口学 内科学 久坐的生活习惯 人口 疾病 横断面研究 屏幕时间 肥胖 环境卫生 病理 社会学
作者
Long H. Nguyen,Morten Schjerven Magnø,Tor Paaske Utheim,Christopher Hammond,Jelle Vehof
出处
期刊:Ocular Surface [Elsevier BV]
卷期号:28: 11-17 被引量:6
标识
DOI:10.1016/j.jtos.2023.01.002
摘要

Sedentary behavior (SB) has been linked with low-grade systemic inflammation, which could play a role in the development of dry eye disease (DED). This cross-sectional study aims to investigate the association between SB and DED. We assessed 48,418 participants from the population-based Lifelines cohort (58% female, 18–96 years). Women's Health Study (WHS)-defined DED was the primary outcome. SB was assessed using the Marshall Sitting Questionnaire. The relationship between DED and SB was analyzed using logistic regressions, corrected for age, sex, BMI, smoking status, demographics, and 48 comorbidities. Any potential modifying effect of physical activity (PA) was also assessed, and the analyses were repeated excluding the most computer-intensive domains, investigating SB independent from screen exposure. WHS-defined DED was present in 9.1% of participants. Greater SB was associated with an increased risk of DED (odds ratio (OR) 1.015 per hour/day, 95%CI 1.005–1.024, P = 0.004). The association between SB and DED was only significant for those with less than WHO-recommended PA (OR 1.022, 95%CI 1.002–1.042, P = 0.027), and not in participants meeting WHO's recommendation (OR 1.011, 95%CI 0.999–1.023, P = 0.076). Lastly, when excluding computer-related sitting, the relationship between SB and DED was attenuated, and no longer significant (OR 1.009, 95%CI 0.996–1.023, P = 0.19). Greater sedentary time was tied to an increased risk of DED, especially for those with lower PA levels than WHO recommendations. However, as there was no significant association when computer-intensive sitting time was excluded, screen use could explain the observed relationship and should be noted as a possible key confounder.
最长约 10秒,即可获得该文献文件

科研通智能强力驱动
Strongly Powered by AbleSci AI
更新
PDF的下载单位、IP信息已删除 (2025-6-4)

科研通是完全免费的文献互助平台,具备全网最快的应助速度,最高的求助完成率。 对每一个文献求助,科研通都将尽心尽力,给求助人一个满意的交代。
实时播报
小欢完成签到,获得积分10
刚刚
小鹅呀完成签到,获得积分10
1秒前
沟通亿心完成签到,获得积分10
1秒前
果果完成签到,获得积分10
2秒前
Panchael完成签到,获得积分10
2秒前
2秒前
小井盖完成签到 ,获得积分10
4秒前
热情的元芹完成签到,获得积分10
4秒前
5秒前
陶醉的小海豚完成签到,获得积分10
6秒前
陆晓亦完成签到,获得积分10
6秒前
乐观的觅松完成签到,获得积分10
6秒前
2023204306324发布了新的文献求助10
7秒前
8秒前
端己完成签到,获得积分20
8秒前
9秒前
阿湫发布了新的文献求助10
9秒前
10秒前
10秒前
坤坤完成签到,获得积分10
10秒前
11秒前
STUSSY完成签到,获得积分10
11秒前
wuhuofeng发布了新的文献求助10
12秒前
13秒前
14秒前
14秒前
coco完成签到,获得积分10
15秒前
lshao完成签到 ,获得积分10
16秒前
16秒前
zhou发布了新的文献求助30
17秒前
跋扈完成签到,获得积分10
19秒前
温柔翰发布了新的文献求助10
19秒前
19秒前
Jj发布了新的文献求助10
20秒前
ficus_min发布了新的文献求助10
20秒前
木子发布了新的文献求助10
21秒前
Galato发布了新的文献求助10
21秒前
寒冷哈密瓜完成签到 ,获得积分0
21秒前
大模型应助shen采纳,获得10
22秒前
123566完成签到,获得积分10
22秒前
高分求助中
【提示信息,请勿应助】关于scihub 10000
Les Mantodea de Guyane: Insecta, Polyneoptera [The Mantids of French Guiana] 3000
徐淮辽南地区新元古代叠层石及生物地层 3000
The Mother of All Tableaux: Order, Equivalence, and Geometry in the Large-scale Structure of Optimality Theory 3000
Global Eyelash Assessment scale (GEA) 1000
Picture Books with Same-sex Parented Families: Unintentional Censorship 550
Research on Disturbance Rejection Control Algorithm for Aerial Operation Robots 500
热门求助领域 (近24小时)
化学 材料科学 医学 生物 工程类 有机化学 生物化学 物理 内科学 纳米技术 计算机科学 化学工程 复合材料 遗传学 基因 物理化学 催化作用 冶金 细胞生物学 免疫学
热门帖子
关注 科研通微信公众号,转发送积分 4038524
求助须知:如何正确求助?哪些是违规求助? 3576221
关于积分的说明 11374737
捐赠科研通 3305912
什么是DOI,文献DOI怎么找? 1819354
邀请新用户注册赠送积分活动 892688
科研通“疑难数据库(出版商)”最低求助积分说明 815048