An enzymatic Finkelstein reaction: fluorinase catalyses direct halogen exchange

The fluorinase enzyme catalyses a direct displacement of bromide and iodide by fluoride ion from 5′-bromodeoxyadenosine and 5′-iododeoxyadenosine respectively to form 5′-fluorodeoxyadenosine in the absence of l-methionine or S-adenosyl-l-methionine.