医学
致盲
甲状腺
食品药品监督管理局
发病机制
甲状腺疾病
眼病
疾病
眼科
皮肤病科
内科学
药理学
临床试验
作者
Raymond S. Douglas,George J. Kahaly,Ami Patel,Saba Sile,Elizabeth H. Thompson,Renee Perdok,James C. Fleming,Brian Fowler,Claudio Marcocci,Michele Marinò,Alessandro Antonelli,Roger A. Dailey,Gerald J. Harris,Anja Eckstein,Jade S. Schiffman,Rosa A. Tang,Christine C. Nelson,Mario Salvi,Sara T. Wester,Jeffrey W. Sherman,Thomas Vescio,Robert J. Holt,Terry J. Smith
标识
DOI：10.1056/nejmoa1910434
摘要
Thyroid eye disease is a debilitating, disfiguring, and potentially blinding periocular condition for which no Food and Drug Administration–approved medical therapy is available. Strong evidence has implicated the insulin-like growth factor I receptor (IGF-IR) in the pathogenesis of this disease.
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