哌醋甲酯
安非他明
医学
痴呆
斯科普斯
精神科
人口
药品
梅德林
注意缺陷多动障碍
内科学
环境卫生
疾病
政治学
法学
多巴胺
作者
Karina Lúcia Moreira Sassi,Natália Pessoa Rocha,Gabriela Delevati Colpo,Vineeth John,Antônio Lúcio Teixeira
出处
期刊:Current Neuropharmacology
[Bentham Science]
日期:2020-01-23
卷期号:18 (2): 126-135
被引量:16
标识
DOI:10.2174/1570159x17666191010093021
摘要
To systematically review the literature on the therapeutic use of amphetamine, lisdexamfetamine and methylphenidate in elderly population with and without dementia.We conducted two researches on the PubMed, Scopus and Embase using the keywords ("elderly") AND ("amphetamine" OR "methylphenidate" OR "lisdexamfetamine") and then ("Alzheimer" OR "dementia") AND ("amphetamine" OR "methylphenidate" OR "lisdexamfetamine").Twenty-nine papers met all the eligibility criteria. The results are encouraging as 81.5% of the studies showed clinical improvement of the investigated condition.Amphetamines and methylphenidate are probably effective strategies for different conditions in the elderly population. However, further studies are needed to provide more robust evidence on efficacy, dosage and safety for this population.
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