As an emerging science now, scientists are attracted toward nanomaterials because of their nanosize, surface area, tunable band gaps, surface morphology as well as potential applications in medicine, medical devices, textile industries, electronic devices, coating industries, and other industries. Herein, we have explained the stable and efficient synthesis protocols and different applications of nanomaterials. This comprehensive review, we feel, will provide insight into the hydrothermal method, sol–gel synthesis, sonochemical method, microwave irradiation method, chemical vapor deposition as well as their various applications. The exceptional properties of nanomaterials make them superior over traditional materials. Therefore, nanomaterials will have a wider application prospect in the future. Research on nanomaterials is significant for the development and application of materials science.