环戊二烯基络合物
铑
对映选择合成
催化作用
化学
平面手性
配体(生物化学)
组合化学
立体化学
有机化学
受体
生物化学
作者
Xiaoqiang Yan,Ji‐Jun Jiang,Jun Wang
标识
DOI:10.1002/ange.202201522
摘要
Abstract Chiral half‐sandwich cyclopentadienyl rhodium(III) (CpRh III ) complexes are powerful catalysts for promoting asymmetric C−H activation reactions. Their preparation normally involved linking or embedding the Cp motif to or into a certain chiral backbone to forge the so‐called chiral Cp ligand. However, preparation of a planar‐chiral CpRh III catalyst bearing a non‐chiral Cp ligand remains a formidable challenge and is rarely reported. We describe herein an unusual class of planar‐chiral rhodium catalysts bearing non‐chiral Cp ligands. Different from existing ones, this catalyst is readily tunable. Ten planar‐chiral only CpRh III catalysts were prepared with ease, and successfully used in two enantioselective C−H activation reactions. Given its convenient synthesis and high structural tunability, these catalysts are expected to find more utilities in asymmetric C−H activation.
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