Cobalt-catalyzed carbonylative synthesis of free (NH)-tetrahydro-β-carbolinones from tryptamine derivatives

A new cobalt-catalyzed carbonylative synthesis of free (NH)-tetrahydro-β-carbolinones from tryptamine derivatives has been developed. A variety of free (NH)-tetrahydro-β-carbolinones were produced in good yields. The oxidant, silver salt, can be recycled and reused.