Effect of the Isoniazide on Guinea Pigs Infected with Isoniazide Resistant Strains of Mycobacterium Tuberculosis

Isoniazide administered for six weeks in the treatment of tuberculosis of the guinea pig infected with isoniazide resistant mycobacterium tuberculosis is effective to the resistance level of 1 mcgm./cc. Above this degree of resistance the progress of the disease is delayed in comparison with the non-treated control animals.