荟萃分析
维生素D与神经学
维生素
医学
维生素D缺乏
内科学
生理学
内分泌学
作者
Shanshan Liu,Xun Zhu,Yuanxin Wang,Shoumeng Yan,Dong Li,Weiwei Cui
标识
DOI:10.1515/jpem-2019-0388
摘要
Abstract The objective of this short communication was the relationship between vitamin D and precocious puberty (PP). In this study, a comprehensive search of multiple databases was performed to identify studies focused on the association between vitamin D deficiency and PP. Studies that compared serum vitamin D levels between patients with PP and controls were selected for the systematic meta-analysis. The main outcome was the mean difference in serum vitamin D levels between PP and controls. Vitamin D-deficient subjects were more likely to develop PP. Our findings suggest that PP may be linked to vitamin D deficiency. Thus, providing supplements of vitamin D to PP patients may improve their nutritional status and prevent diseases. But, the amount of vitamin D required is uncertain, so it is important to be careful when taking vitamin D supplements.
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