Diagnosis strategy of Guillain-Barré syndrome spectrum disorders

Guillain-Barre syndrome(GBS) has clinical characteristics: flaccid, symmetrical, ascending paralysis.Cranial nerves and respiratory muscle related, albuminocytologic dissociation in cerebrospinal fluid, and electrophysiological changes.GBS was believed to be an autoimmune perineuropathy.Recently, there were more and more reports about GBS spectrum disorders or GBS variant correlated with anti-GQ1b antibody or anti-GM1 IgG antibody et al.The GBS Classification Group presented the new clinical criteria in 2014, to enable neurologists and non-neurologists to diagnose GBS and all its variants using a simple yet all-inclusive classification system. Key words: Guillain-Barre syndrome spectrum disorders; Guillain-Barre syndrome variant; Anti-GQ1b antibody; Anti-GM1 IgG antibody; Miller-Fisher syndrome