聚酯纤维
聚合
药物输送
聚合物
纳米技术
材料科学
开环聚合
化学
高分子科学
有机化学
作者
Ann‐Christine Albertsson,I. K. Varma
出处
期刊:Biomacromolecules
[American Chemical Society]
日期:2003-10-23
卷期号:4 (6): 1466-1486
被引量:1448
摘要
Aliphatic polyesters prepared by ring-opening polymerization of lactones are now used worldwide as bioresorbable devices in surgery (orthopaedic devices, sutures, stents, tissue engineering, and adhesion barriers) and in pharmacology (control drug delivery). This review presents the various methods of the synthesis of polyesters and tailoring the properties by proper control of molecular weight, composition, and architecture so as to meet the stringent requirements of devices in the medical field. The effect of structure on properties and degradation has been discussed. The applications of these polymers in the biomedical field are described in detail.
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