Cyclic ureas (DMI, DMPU) as efficient, sustainable ligands in iron-catalyzed C(sp2)–C(sp3) coupling of aryl chlorides and tosylates

We report that cyclic ureas (DMI, DMPU) are efficient and sustainable alternatives to reprotoxic NMP in challenging iron-catalyzed C(sp²)–C(sp³) alkylations of aryl chlorides and tosylates with alkyl Grignard reagents.